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THE TEMPORARY SECOND SKIN

Shift to Synthetics

SUPRATHEL® is a proven synthetic skin substitute that has revolutionized the treatment of epidermal and dermal wounds. Since its launch more than 20 years ago, it has significantly influenced the switch to synthetic products and is now used in more than 40 countries worldwide as a standard treatment for second-degree burn wounds and split thickness skin graft (STSG) donor sites.

Like a second skin

Like a second skin, SUPRATHEL® gently covers the wound and promotes rapid, complication-free healing. Developed analogously to the human skin, SUPRATHEL® has the same important properties such as elasticity, water vapour permeability and impermeability to bacteria.

Single application

SUPRATHEL® is applied only once to the previously cleaned, debrided, and disinfected wound and remains there until complete healing. After application, the membrane becomes transparent and allows the healing process to be evaluated.

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Scald (hand)

Patient: Male, 5 years old
Outcome: Complete epithelization by day 12 with full range of motion

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Re-harvesting at donor site

Patient: Male, 13 years old
Outcome: At 3.5 year follow-up, the repeatedly harvested donor site demonstrated favorable long-term scar quality

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Scald (body)

Patient: Male, 38 years old
Outcome: Survival with complete re-epithelialization across nearly all affected areas, only 7% TBSA required CEA coverage

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Toxic Epidermal Necrolysis (TEN)

Patient: Female, 48 years old
Outcome: Nearly complete re-epithelization by 4 weeks

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Electrical burn

Patient: Male, 59 years old
Outcome: Complete re-epithelization with re-pigmentation and minimal scarring

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Indications

SUPRATHEL® is intended for the treatment of wounds that include:

  • Epidermal and dermal wounds
  • Split-thickness skin graft (STSG) donor sites
  • Second-degree burn areas (2a/2b)
  • Second-degree burns mixed with 3rd degree burned areas
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Benefits

Single application, no change of SUPRATHEL® necessary

Significant pain relief 1-4 – up to 60%

  • Less anesthesia and pain medication required1,5-6

Low rate of infections1,2,5,7-9, no biologic risk

  • Synthetic, biocompatible, absorbable
  • No reported allergic reactions

Fast wound healing1,2,5

  • Improved epithelialization3-11

Lower treatment costs2,4,5

  • Less cost and effort for dressing changes2,9
  • Shorter hospital stay5

Excellent cosmetic outcomes and scar quality4,7,8

Low inflammatory reaction12

Reduced transplantation rate6

Composition

SUPRATHEL® is purely synthetic and therefore does not bear any residual risks as can be the case with biological products of human or animal origin. Upon final resorption, PMI’s PLA Technology leaves only CO2 and H2O in the wound bed.

Polymer:
Lactide-based copolymer

Degradation:
Hydrolytic (to CO2 and H2O)

Permeability to water vapor:
40 – 70 ml/m2 per hour, 1,000 – 1,700 ml/m2 per day

Porosity:
70% – 80%

Supporting materials

Contact your local representative for additional materials.

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Size#

Quantity#

5×5 cm

5

9×10 cm

1

9×10 cm

5

18×10 cm

1

18×10 cm

5

18×23 cm

1

18×23 cm

5

Face Mask*

1

Hand Shape*

2

“SUPRATHEL® represents an integral armamentarium in burn
surgery.”

Lect. MD. Lars-Peter Kamolz, M. Sc, Vienna

1 Schwarze et al. Burns. 2007 Nov;33(7):850-4 | 2 Schwarze et al. Ann Plast Surg. 2008 Feb;60(2):181-5 | 3 Uhlig et al. Burns. 2007 Mar;33(2):221-9 | 4 Kaartinen et al. J Plast Surg Hand Surg. 2011 Sep;45(4-5):200-3 | 5 Everett et al. J Wound Care. 2015 Jul;24(7):S4-8 | 6 Schriek et al. Eur Burn J. 2022 Dec;3(1):1–9 | 7 Keck et al. Burns. 2012 May;38(3):388-95 | 8 Hundeshagen et al. J Burn Care Res. 2018 Feb 20;39(2):261-7 | 9 Markl et al. Ann Plast Surg. 2010 Nov;65(5):490-6 | 10 Gurunluoglu et al. J Burn Care Res. 2019 Jun 21;40(4):444-50 | 11 Gurunluoglu et al. J Burn Care Res. 2019 Apr 26;40(3):302-11 | 12 Demircan et al. Ulus Travma Acil Cerrahi Derg. 2021 Jan;27(1):122-31