SYNTHETIC GUIDED WOUND CLOSURE MATRIX
Limb salvage
Patient: Male, 60 years
Etiology: Deep abscess of the left foot
Comorbidities: Type 2 diabetes mellitus, heart failure, peripheral arterial disease
Source: Dr. Brock A Liden, WAFL, U.S.A.; presented at EWMA 2024, U.K.
Initial Presentation, after a deep abscess drainage of the foot, systemic antibiotic therapy, and local use of antibiotic cement, this patient presented with a 25 cm² wound with extensive necrotic tissue. The devitalized tissue was excised and SUPRA SDRM® was applied to fill the defect.
Week 5, after 4 weekly applications, the wound bed presented granulation tissue that covered all previously exposed tendons. The wound size recorded was 9.51 cm², representing a 62% reduction in size. Note how the fourth toe has completely healed and its amputation avoided.
Week 12, after 10 weekly applications, the wound was completely healed. The patient regained full function with adequate toe mobility and no pain on ambulation.
Diabetic ulcer
Patient: Male, 69 years
Etiology: Ulcer present for 6 months, other treatment modalities failed to close
Comorbidities: Type 2 diabetes mellitus
Source: Dr. Matthew Regulski, Wound Care Institute of Ocean County, U.S.A.
Baseline
Week 4
Week 6
Week 7
Week 8
Pyoderma gangrenosum
Patient: Female, 71 years
Etiology: Chronic pyoderma gangrenosum ulcer (duration: 2 years)
Source: Dr. Matthew Regulski, Wound Care Institute of Ocean County, U.S.A.; presented at SAWC Spring 2024
Baseline
Week 4, the ulcer size had reduced by over 80% and the inflammatory halo was greatly reduced.
Week 5
Week 7
Week 8, complete healing was achieved with minimal scarring and no signs of soft tissue residual inflammation.
Venous leg ulcer
Patient: Male, 70 years
Etiology: Right lower extremity ulceration, treated for 4 months prior with no change in wound size
Comorbidities: Soft tissue trauma, lymphedema, venous insufficiency
Source: Emily Ray, DO, CWSP, APWH; Christina Sikes, DO; Joan Hughes, BSN, RN Hamilton Wound Care and Hyperbaric Center, GA
Baseline
